Ribosomal Protein L15 is involved in Colon Carcinogenesis
نویسندگان
چکیده
منابع مشابه
Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo
Protein kinase C iota (PKCiota) has been implicated in Ras signaling, however, a role for PKCiota in oncogenic Ras-mediated transformation has not been established. Here, we show that PKCiota is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively active PKCiota in the colon are highly susceptible to carcinogen-induced colon carcin...
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ژورنال
عنوان ژورنال: International Journal of Medical Sciences
سال: 2019
ISSN: 1449-1907
DOI: 10.7150/ijms.34386